BDBM356604 N-(3-{7-[1-(2-Cyano-1-phenylethyl)-1H-pyrazol-4-yl]imidazo[1,2-b]pyridazin-3-yl}phenyl)-N′-(2,2,2-trifluoroethyl)urea::US10213427, Example 93::US10813930, Ex. No. 93

SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(cnn12)-c1cnn(c1)C(CC#N)c1ccccc1

InChI Key InChIKey=UQWLWPSKDYCCCO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356604   

TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM356604(N-(3-{7-[1-(2-Cyano-1-phenylethyl)-1H-pyrazol-4-yl...)
Affinity DataIC50: <10nMAssay Description:FGFR3 Enzymatic Assay The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM356604(N-(3-{7-[1-(2-Cyano-1-phenylethyl)-1H-pyrazol-4-yl...)
Affinity DataIC50: <10nMAssay Description:The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent