BDBM356638 1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl) tetrahydropyrimidin- 2(1H)-one::US10214507, Compound 3::US10759777, Compound 3

SMILES OC(CN1CCCNC1=O)Cn1c2ccccc2c2ccccc12

InChI Key InChIKey=BUGJWJMFMGQEPL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356638   

TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356638(1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl) tetrahy...)
Affinity DataEC50:  299nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356638(1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl) tetrahy...)
Affinity DataEC50:  299nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent