BDBM356653 1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypropyl)-3- fluoropyrrolidin-2- one::US10214507, Compound 9::US10759777, Compound 9
SMILES OC(CN1CCC(F)C1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12
InChI Key InChIKey=CTLHGLZELHMPOK-UHFFFAOYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 356653
Affinity DataEC50: 300nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
Affinity DataEC50: 208nMAssay Description:Modulation activity at CRY2/PER2 in human U2OS cells harboring per2-dLuc assessed as activation of per2 activity measured every 100 mins for 5 days b...More data for this Ligand-Target Pair