BDBM35671 benzazepinelidene acetamide derivative, 1f

SMILES C[C@H]1CCN(C1)c1ccc(C(=O)N2CCC(F)(F)\C(=C/C(=O)NCCO)c3ccccc23)c(Cl)c1

InChI Key InChIKey=SALSRQVDZRKOPL-SZHLLGMXSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35671   

TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35671(benzazepinelidene acetamide derivative, 1f)
Affinity DataKi:  14nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35671(benzazepinelidene acetamide derivative, 1f)
Affinity DataKi:  17nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed