BDBM35689 5H-1-benzazepin-5-ylidene acetamide, 1q

SMILES Cc1ccn(n1)-c1ccc(C(=O)N2CCC(F)(F)\C(=C/C(O)=O)c3ccccc23)c(Cl)c1

InChI Key InChIKey=WWYOUXCBBIIJAP-AQTBWJFISA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35689   

TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35689(5H-1-benzazepin-5-ylidene acetamide, 1q)
Affinity DataKi:  25nM ΔG°:  -10.3kcal/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35689(5H-1-benzazepin-5-ylidene acetamide, 1q)
Affinity DataKi:  6.30E+3nM ΔG°:  -7.09kcal/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed