BDBM357914 2-Amino-8-fluoro-7-isopropyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid::US10214536, Compound 272
SMILES CC(C)c1cc2c(cc1F)oc1nc(N)c(cc1c2=O)C(O)=O
InChI Key InChIKey=ZAFOQCLNYNBOQC-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 357914
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataIC50: 1.24E+3nMAssay Description:Kinase assays are commonly used for determining the ability of a small molecule to inhibit enzyme activity. By measuring the degree of phosphorylatio...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human IKKepsilon (1 to 655 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in pres...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 5.37E+3nMAssay Description:Inhibition of human IKKepsilon (1 to 655 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in pres...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataIC50: 398nMAssay Description:Inhibition of human TBK1 (1 to 657 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in presence o...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataIC50: 400nMAssay Description:Inhibition of human TBK1 (1 to 657 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in presence o...More data for this Ligand-Target Pair