BDBM358663 3-(2-(4-(3-(4-amino-5-chloropyrrolo [2,1-f][1,2,4]triazin-7-yl)phenyl)-2,2- dimethyl-3-oxopiperazin-1-yl)-2- oxoethyl)oxazolidin-2-one::US10214537, Example 740
SMILES CC1(C)N(CCN(C1=O)c1cccc(c1)-c1cc(Cl)c2c(N)ncnn12)C(=O)CN1CCOC1=O
InChI Key InChIKey=KKPIFVUMLXYYJY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358663
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 0.5nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair