BDBM358687 4-(4-amino-5-(trifluoromethyl)pyrrolo [2,1-f][1,2,4]triazin-7-yl)-2-(4-(2-(4,4- dimethyl-2-oxopyrrolidin-1-yl)acetyl)- 3,3-dimethyl-2-oxopiperaizn-1- yl)benzonitrile::US10214537, Example 765

SMILES CC1(C)CN(CC(=O)N2CCN(C(=O)C2(C)C)c2cc(ccc2C#N)-c2cc(c3c(N)ncnn23)C(F)(F)F)C(=O)C1

InChI Key InChIKey=YWXLHEPUCBLULY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358687   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM358687(4-(4-amino-5-(trifluoromethyl)pyrrolo [2,1-f][1,2,...)
Affinity DataIC50:  0.400nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent