BDBM358690 N-(2-(4-(5-(4-amino-5- (trifluoromethyl)pyrrolo[2,1-f][1,2,4] triazin-7-yl)-2-cyanophenyl)-2,2- dimethyl-3-oxopiperazin-1-yl)-2- oxoethyl)methanesulfonamide::US10214537, Example 768
SMILES CC1(C)N(CCN(C1=O)c1cc(ccc1C#N)-c1cc(c2c(N)ncnn12)C(F)(F)F)C(=O)CNS(C)(=O)=O
InChI Key InChIKey=ZFQNJJWNLFSSGB-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358690
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 0.200nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair