BDBM358914 (6R,8aS)-6-(8-amino-1- {4-[(1R)-1-hydroxy-1-(3- methoxyphenyl)ethyl] phenyl}imidazo[1,5- a]pyrazin-3- yl)hexahydroindolizin- 3(2H)-one::US10214546, Example 45
SMILES COc1cccc(c1)[C@](C)(O)c1ccc(cc1)-c1nc([C@@H]2CC[C@H]3CCC(=O)N3C2)n2ccnc(N)c12
InChI Key InChIKey=PZNCCKBPRSSKCV-GUDDLILSSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358914
Affinity DataIC50: 1.10nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair