BDBM358966 (6R,8aS)-6-(8-amino-1- {4-[(1R)-1-(3- cyclopropylphenyl)-1- hydroxyethyl]-3- methoxyphenyl}imidazo [1,5-a]pyrazin-3- yl)hexahydroindolizin- 3(2H)-one::US10214546, Example 98
SMILES COc1cc(ccc1[C@](C)(O)c1cccc(c1)C1CC1)-c1nc([C@@H]2CC[C@H]3CCC(=O)N3C2)n2ccnc(N)c12
InChI Key InChIKey=HUFWGNOUYCORNX-QVVQTHAHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358966
Affinity DataIC50: 0.280nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair