BDBM358989 (6R,8aS)-6-[8-amino-5- chloro-1-(4-{(1R)-1- hydroxy-1-[3-(2,2,2- trifluoroethyl)phenyl] ethyl}phenyl)imidazo[1,5- a]pyrazin-3- yl]hexahydroindolizin- 3(2H)-one::US10214546, Example 121
SMILES C[C@@](O)(c1ccc(cc1)-c1nc([C@@H]2CC[C@H]3CCC(=O)N3C2)n2c(Cl)cnc(N)c12)c1cccc(CC(F)(F)F)c1
InChI Key InChIKey=DTHHDLICAQVDEJ-GUDDLILSSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358989
Affinity DataIC50: 0.180nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair