BDBM359008 (6R,8aS)-6-[8-amino-5- chloro-1-(4-{(1R)-1-[3-(1,1- difluoroethyl)phenyl)-1- hydroxyethyl}(phenyl) imidazo[1,5-a]pyrazin-3- yl)hexahydroindolizin- 3(2H)-one::US10214546, Example 140
SMILES CC(F)(F)c1cccc(c1)[C@](C)(O)c1ccc(cc1)-c1nc([C@@H]2CC[C@H]3CCC(=O)N3C2)n2c(Cl)cnc(N)c12
InChI Key InChIKey=CJDBZHSKQJVNHQ-WACOAXRMSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 359008
Affinity DataIC50: 0.220nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair