BDBM359012 (6R,8aS)-6-[8-amino-1- (4-{1-[3- (difluoromethoxy)phenyl]- 1-hydroxyethyl}phenyl) imidazo[1,5-a]pyrazin-3- yl]hexahydroindolizin- 3(2H)-one::US10214546, Example 144::US10214546, Example 148
SMILES CC(O)(c1ccc(cc1)-c1nc([C@@H]2CC[C@H]3CCC(=O)N3C2)n2ccnc(N)c12)c1cccc(OC(F)F)c1
InChI Key InChIKey=AWSYJQHGDFQVQU-VGEZZCLVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 359012
Affinity DataIC50: 0.200nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Affinity DataIC50: 67.6nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair