BDBM359046 (6R.8aS)-6-[8-amino-1- (4-{(1R)-1-[3- (difluoromethyl)phenyl]-1- hydroxyethyl}phenyl)- 5-fluoroimidazo[1,5- a]pyrazin-3-yl]-2,2- dimethylhexahydroindolizin- 3(2H)-one::US10214546, Example 178
SMILES C[C@@](O)(c1ccc(cc1)-c1nc([C@@H]2CC[C@H]3CC(C)(C)C(=O)N3C2)n2c(F)cnc(N)c12)c1cccc(c1)C(F)F
InChI Key InChIKey=JBGGEYBUAOOWQE-MNSNBHKMSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 359046
Affinity DataIC50: 1.30nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair