BDBM359050 (1R,6R,8aS)-6-[8- amino-1-(4-{(1R)-1-[3- (difluoromethyl)phenyl]-1- hydroxyethyl}phenyl) imidazo[1,5-a]pyrazin- 3-yl]-1- (trifluoromethyl) hexahydroindolizin-3(2H)- one::US10214546, Example 182::US10214546, Example 184
SMILES C[C@@](O)(c1ccc(cc1)-c1nc([C@@H]2CC[C@H]3C(CC(=O)N3C2)C(F)(F)F)n2ccnc(N)c12)c1cccc(c1)C(F)F
InChI Key InChIKey=FUZSNLSJUYKJHS-VYKGGNLFSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 359050
Affinity DataIC50: 1.40nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair