BDBM359054 (6R,8aS)-6-[8-amino-1- (2-ethoxy-4-{(1S)-1- hydroxy-1-[3- (trifluoromethyl)phenyl] ethyl}phenyl)imidazo [1,5-a]pyrazin-3-yl]-1,1- dimethylhexahydroindolizin- 3(2H)-one::US10214546, Example 186
SMILES CCOc1cc(ccc1-c1nc([C@@H]2CC[C@@H]3N(C2)C(=O)CC3(C)C)n2ccnc(N)c12)[C@@](C)(O)c1cccc(c1)C(F)(F)F
InChI Key InChIKey=IOQOSFYXDORMQO-RNUBLEDQSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 359054
Affinity DataIC50: 1.30nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair