BDBM359060 (6R,8aS)-6-(8-amino-1- (4-{1-[3- (difluoromethyl)phenyl]- 1-hydroxyethyl}-2- fluorophenyl)imidazo[1,5- a]pyrazin-3- yl]hexahydroindolizin- 3(2H)-one::US10214546, Example 192::US10214546, Example 195
SMILES CC(O)(c1cccc(c1)C(F)F)c1ccc(-c2nc([C@@H]3CC[C@H]4CCC(=O)N4C3)n3ccnc(N)c23)c(F)c1
InChI Key InChIKey=JNSWNWHOSPVKDN-OWZGVKFESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 359060
Affinity DataIC50: 0.330nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair