BDBM359081 (6R,8aS)-6-[8-amino-1- (2-ethoxy-6-fluoro-4- {(1R)-1-hydroxy-1-[3- (trifluoromethyl)phenyl] ethyl}phenyl)imidazo [1,5-a]pyrazin-3- yl]hexahydroindolizin- 3(2H)-one::US10214546, Example 213
SMILES CCOc1cc(cc(F)c1-c1nc([C@@H]2CC[C@H]3CCC(=O)N3C2)n2ccnc(N)c12)[C@](C)(O)c1cccc(c1)C(F)(F)F
InChI Key InChIKey=BYYSVLQJGDDQJV-XHEIURJNSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 359081
Affinity DataIC50: 0.630nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair