BDBM359893 N-(4-((3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperidin-1-yl)pyridin-3-yl)-3-(2,6-difluoro-3-methoxyphenyl)furo[3,2-b]pyridine-5-carboxamide::US9822124, Example 13
SMILES COc1ccc(F)c(-c2coc3ccc(nc23)C(=O)Nc2cnccc2N2C[C@H](C)[C@@H](O)[C@H](N)C2)c1F
InChI Key InChIKey=CSTUZQWUTYUKJM-DXRUEXFKSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 359893
Affinity DataIC50: <10nMAssay Description:Pim-1 and Pim-3 kinase assays 20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Pim-1 and Pim-3 kinase assays 20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Pim-2 kinase assay20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay buffer ...More data for this Ligand-Target Pair