BDBM361044 (S)—N1-(1-amino-3-hydroxypropan-2-yl)-4-(2-aminobenzo[d]thiazol-4-yl)-3-(1H-tetrazol-5-yl)benzene-1,2-disulfonamide::US10221163, Example 201::US10544130, Example 201

SMILES NCC(CO)NS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 361044   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361044((S)—N1-(1-amino-3-hydroxypropan-2-yl)-4-(2-am...)
Affinity DataIC50:  0.109nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361044((S)—N1-(1-amino-3-hydroxypropan-2-yl)-4-(2-am...)
Affinity DataIC50:  0.0200nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase()
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361044((S)—N1-(1-amino-3-hydroxypropan-2-yl)-4-(2-am...)
Affinity DataIC50:  0.125nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361044((S)—N1-(1-amino-3-hydroxypropan-2-yl)-4-(2-am...)
Affinity DataIC50:  0.109nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361044((S)—N1-(1-amino-3-hydroxypropan-2-yl)-4-(2-am...)
Affinity DataIC50:  0.0200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361044((S)—N1-(1-amino-3-hydroxypropan-2-yl)-4-(2-am...)
Affinity DataIC50:  0.125nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent