BDBM361587 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(4-chlorophenyl)spiro[3.5]non-6-en-7- yl)methyl)piperazin-1-yl)-N-((7-nitro-1- ((tetrahydro-2H-pyran-4-yl)methyl)-1H- indazol-5-yl)sulfonyl)benzamide::US10221174, Compound 60::US10829488, Compound 60::US11718613, Compound 60
SMILES [O-][N+](=O)c1cc(cc2cnn(CC3CCOCC3)c12)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCN(CC2=C(CC3(CCC3)CC2)c2ccc(Cl)cc2)CC1
InChI Key InChIKey=NQBVBWKJACFSJH-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 361587
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataIC50: 2.10nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataIC50: 67.5nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
TargetBcl-2-like protein 11 [81-106](Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataIC50: 67.5nMAssay Description:Bcl-2 and Bcl-xL Inhibition: Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respect...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataIC50: 2.10nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
TargetBcl-2-like protein 11 [72-87](Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataIC50: 2.10nMAssay Description:Bcl-2 and Bcl-xL Inhibition: Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respect...More data for this Ligand-Target Pair