BDBM362654 (4S)-7-(3,5-dimethylisoxazol-4-yl)-2-[(3S)- 4-isobutyryl-3-methylpiperazin-1-yl]-4- pyridin-2-yl-4,5-dihydroimidazo[1,5,4- de][1,4]benzoxazine::US10227359, Example 9::US9834565, Example 9
SMILES CC(C)C(=O)N1CCN(C[C@@H]1C)c1nc2ccc(-c3c(C)noc3C)c3OC[C@H](c4ccccn4)n1c23
InChI Key InChIKey=QVFNWZZKUKTJTE-GAJHUEQPSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 362654
Affinity DataIC50: <25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: <25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: <25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: <25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair