BDBM363224 (S)-4-(4-(2-chloro-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzyloxy)-2-(3-cyanobenzyloxy)benzylamino)-3-hydroxybutanoic acid::US9850225, Example 1147

SMILES O[C@H](CNCc1ccc(OCc2cccc(c2Cl)-c2ccc3OCCOc3c2)cc1OCc1cccc(c1)C#N)CC(O)=O

InChI Key InChIKey=IUZNQSQFZZQRBZ-MHZLTWQESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363224   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363224((S)-4-(4-(2-chloro-3-(2,3-dihydrobenzo[b][1,4]diox...)
Affinity DataIC50:  5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent