BDBM363278 (2S,4R)-1-(5-chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)benzyl)-4-hydroxypyrrolidine-2-carboxylic acid::US9850225, Example 1197

SMILES Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3C[C@H](O)C[C@H]3C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1

InChI Key InChIKey=QBXVXKRWOVBUDB-MVSFAKPFSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363278   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363278((2S,4R)-1-(5-chloro-2-((3-cyanobenzyl)oxy)-4-((3-(...)
Affinity DataIC50:  1.85nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair