BDBM363448 (S)-2-((5-chloro-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-2-((5-((ethoxycarbonyl)amino)pyridin-3-yl)methoxy)benzyl)amino)-3-hydroxy-2-methylpropanoic acid::US9850225, Example 3009

SMILES CCOC(=O)Nc1cncc(COc2cc(OCc3cccc(c3C)-c3ccc4OCCOc4c3)c(Cl)cc2CN[C@@](C)(CO)C(O)=O)c1

InChI Key InChIKey=NQDDFZIGVCAALU-BHVANESWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363448   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363448((S)-2-((5-chloro-4-((3-(2,3-dihydrobenzo[b][1,4]di...)
Affinity DataIC50:  5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent