BDBM36350 6-[4-(Trifluoromethyl)phenyl]-3,4-dihydro-2(1H)-quinolinone::CID12000936::GSK-1
SMILES FC(F)(F)c1ccc(cc1)-c1ccc2NC(=O)CCc2c1
InChI Key InChIKey=WNVWLPPJRMIRBG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 36350
Affinity DataKi: 1.70nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataKi: 66nMpH: 6.8Assay Description:wild-type HCT116 selected at 6WT-6x the IC95More data for this Ligand-Target Pair
Affinity DataKi: 109nMpH: 6.8Assay Description:wild-type HCT116 selected at 3 the IC95More data for this Ligand-Target Pair
Affinity DataIC50: 2.09E+3nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 162nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair