BDBM36361 CID16202134::Pladienolide analog 9

SMILES CC[C@H](O)[C@@H](C)[C@H]1O[C@@H]1C[C@H](C)\C=C\C=C(/C)[C@H]1OC(=O)C[C@H](O)CC[C@@](C)(O)[C@@H](OC(=O)NCCOCCOCCNC(=O)CCCCC2=[N+]3C(C=C2)=Cc2c(C)cc(C)n2[B-]3(F)F)\C=C\[C@@H]1C

InChI Key InChIKey=DPYKTDAKHXJBCZ-PQKOXMGWSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36361   

TargetSplicing factor 3B subunit 3(Homo sapiens (Human))
Eisai

LigandPNGBDBM36361(CID16202134 | Pladienolide analog 9)
Affinity DataEC50:  78.4nMpH: 7.8 T: 2°CAssay Description:Placental alkaline phosphatase (PLAP) reporter assay controlled by VEGF promoter (VEGF-PLAP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSplicing factor 3B subunit 3(Homo sapiens (Human))
Eisai

LigandPNGBDBM36361(CID16202134 | Pladienolide analog 9)
Affinity DataEC50:  70.2nMpH: 7.8 T: 2°CAssay Description:Cell proliferation assay using WiDrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSplicing factor 3B subunit 3(Homo sapiens (Human))
Eisai

LigandPNGBDBM36361(CID16202134 | Pladienolide analog 9)
Affinity DataEC50:  645nMpH: 7.8 T: 2°CAssay Description:Placental alkaline phosphatase (PLAP) reporter assay controlled by VEGF promoter (VEGF-PLAP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed