BDBM36403 (3R)-3-(1,2,3,4-Tetrahydroisoquinolin-7-yloxymethyl)-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine, 16::CID24894155

SMILES NC1=N[C@H](COc2ccc3CCNCc3c2)COc2ccsc12

InChI Key InChIKey=UDFXWCLBONUMNA-CYBMUJFWSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36403   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36403((3R)-3-(1,2,3,4-Tetrahydroisoquinolin-7-yloxymethy...)
Affinity DataIC50:  400nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36403((3R)-3-(1,2,3,4-Tetrahydroisoquinolin-7-yloxymethy...)
Affinity DataIC50:  1.00E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36403((3R)-3-(1,2,3,4-Tetrahydroisoquinolin-7-yloxymethy...)
Affinity DataIC50:  5.00E+4nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed