BDBM364411 US10913711, Compound 4i::US11555013, Compound 4i::US9862679, Compound 4i

SMILES Brc1ccc(cc1)C(SCCNCCCc1ccccc1)c1ccc(Br)cc1

InChI Key InChIKey=OQRQLSXKDJYXQN-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 364411   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  163nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  163nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  163nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  163nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat brain SERT after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  613nMAssay Description:Displacement of [3H]WIN35,428 from Sprague-Dawley rat brain DAT after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  618nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  618nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  618nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The United States of America, As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health

US Patent
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  3.18E+3nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, frontal cortex dissected and rapidly frozen. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuroepithelial cell-transforming 1(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  3.18E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The United States of America, As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health

US Patent
LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)
Affinity DataKi:  3.18E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent