BDBM367615 Methyl N-[(1S)-2-[4-[2-(4-amino-6-chloro-2-methyl-pyrimidin-5-yl)ethyl]-1-piperidyl]-1-methyl-2-oxo-ethyl]carbamate::US10227310, Example 71

SMILES COC(=O)N[C@@H](C)C(=O)N1CCC(CCc2c(N)nc(C)nc2Cl)CC1

InChI Key InChIKey=CTAGBUIPLIEQID-JTQLQIEISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367615   

TargetGhrelin O-acyltransferase(Homo sapiens (Human))
National Institute On Alcohol Abuse And Alcoholism

Curated by ChEMBL
LigandPNGBDBM367615(Methyl N-[(1S)-2-[4-[2-(4-amino-6-chloro-2-methyl-...)
Affinity DataIC50:  149nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGhrelin O-acyltransferase(Homo sapiens (Human))
National Institute On Alcohol Abuse And Alcoholism

Curated by ChEMBL
LigandPNGBDBM367615(Methyl N-[(1S)-2-[4-[2-(4-amino-6-chloro-2-methyl-...)
Affinity DataIC50:  149nMAssay Description:Prepare test compounds in DMSO to make up a 0.2 mM stock solution. Serially dilute the stock solution in DMSO for ten concentrations with final compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent