BDBM367643 N-((1R,2R)-1-(3-chloro-4- cyclopropoxyphenyl)-1-hydroxy-3- (pyrrolidin-1-yl)propan-2-yl)-8-fluoro- 1H-naphtho[2,1-d][1,2]oxazine-4- carboxamide::US10227312, Example 28::US10759769, Example 28
SMILES O[C@@H]([C@@H](CN1CCCC1)NC(=O)C1=NOCc2c1ccc1cc(F)ccc21)c1ccc(OC2CC2)c(Cl)c1
InChI Key InChIKey=PCVUWXGOSVAZHD-LEAFIULHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 367643
Affinity DataIC50: 5.5nMAssay Description:Protein concentration was determined using BCA assay kit. Sixty micrograms of MDCK cell lysate was incubated with various concentrations of a compoun...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair