BDBM367647 8-chloro-N-((1R,2R)-1-(3-chloro-4- cyclopropoxyphenyl)-1-hydroxy-3- (pyrrolidin-1-yl)propan-2-yl)-1H- thieno[3',2':3,4]benzo[1,2- d][1,2]oxazine-4-carboxamide::US10227312, Example 32::US10759769, Example 32
SMILES O[C@@H]([C@@H](CN1CCCC1)NC(=O)C1=NOCc2c1ccc1sc(Cl)cc21)c1ccc(OC2CC2)c(Cl)c1
InChI Key InChIKey=UYGPAPGAXHYKTH-QFQXNSOFSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 367647
Affinity DataIC50: 5.5nMAssay Description:Protein concentration was determined using BCA assay kit. Sixty micrograms of MDCK cell lysate was incubated with various concentrations of a compoun...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair