BDBM367845 3-(2-amino-7- methylbenzo[d]thiazol-4- yl)-6-(azetidin-3- ylsulfonyl)-2-(2H-tetrazol- 5-yl)benzenesulfonamide::US10227331, Example 32

SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)C2CNC2)c2nc(N)sc12

InChI Key InChIKey=FENLKZTUOZTGHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367845   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367845(3-(2-amino-7- methylbenzo[d]thiazol-4- yl)-6-(azet...)
Affinity DataIC50:  0.138nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367845(3-(2-amino-7- methylbenzo[d]thiazol-4- yl)-6-(azet...)
Affinity DataIC50:  0.106nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367845(3-(2-amino-7- methylbenzo[d]thiazol-4- yl)-6-(azet...)
Affinity DataIC50:  0.0330nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent