BDBM367854 3-(2-amino-3H- benzo[d]imidazol-5-yl)-6- (piperidin-4-ylsulfonyl)-2- (2H-tetrazol-5- yl)benzenesulfonamide::US10227331, Example 41

SMILES Nc1nc2ccc(cc2[nH]1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)C1CCNCC1

InChI Key InChIKey=PNRBCPLTLJCAJE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367854   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367854(3-(2-amino-3H- benzo[d]imidazol-5-yl)-6- (piperidi...)
Affinity DataIC50:  3.51nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367854(3-(2-amino-3H- benzo[d]imidazol-5-yl)-6- (piperidi...)
Affinity DataIC50:  0.171nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367854(3-(2-amino-3H- benzo[d]imidazol-5-yl)-6- (piperidi...)
Affinity DataIC50:  0.535nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent