BDBM367858 3-(2-amino-3H-benzo[d]imidazol-4-yl)-6- (1-(methylsulfonyl)piperidin-4- ylsulfonyl)-2-(2H-tetrazol-5- yl)benzenesulfonamide::US10227331, Example 45

SMILES CS(=O)(=O)N1CCC(CC1)S(=O)(=O)c1ccc(-c2cccc3nc(N)[nH]c23)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key InChIKey=URWJAEFBDOHZMD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367858   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367858(3-(2-amino-3H-benzo[d]imidazol-4-yl)-6- (1-(methyl...)
Affinity DataIC50:  1.69nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367858(3-(2-amino-3H-benzo[d]imidazol-4-yl)-6- (1-(methyl...)
Affinity DataIC50:  0.135nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367858(3-(2-amino-3H-benzo[d]imidazol-4-yl)-6- (1-(methyl...)
Affinity DataIC50:  0.290nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent