BDBM367903 6-(2-aminoethylsulfonyl)-3-(2-(methylamino)benzo[d]thiazol-4-yl)-2-(2H-tetrazol-5-yl)benzene sulfonamide::US10227331, Example 90

SMILES CNc1nc2c(cccc2s1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)CCN

InChI Key InChIKey=NSGMUFSUDIXAJY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367903   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367903(6-(2-aminoethylsulfonyl)-3-(2-(methylamino)benzo[d...)
Affinity DataIC50:  0.0990nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367903(6-(2-aminoethylsulfonyl)-3-(2-(methylamino)benzo[d...)
Affinity DataIC50:  0.146nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367903(6-(2-aminoethylsulfonyl)-3-(2-(methylamino)benzo[d...)
Affinity DataIC50:  0.0750nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent