BDBM367926 3-((4-(1-oxoisoindolin-4- yl)-2-sulfamoyl-3-(1H- tetrazol-5- yl)phenyl)sulfonyl)azetidin- 1-ium 2,2,2- trifluoroacetate::US10227331, Example 113

SMILES NS(=O)(=O)c1c(ccc(-c2cccc3C(=O)NCc23)c1-c1nnn[nH]1)S(=O)(=O)C1CNC1

InChI Key InChIKey=GQGAVJZBXQWLHQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367926   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367926(3-((4-(1-oxoisoindolin-4- yl)-2-sulfamoyl-3-(1H- t...)
Affinity DataIC50:  6.06nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367926(3-((4-(1-oxoisoindolin-4- yl)-2-sulfamoyl-3-(1H- t...)
Affinity DataIC50:  0.164nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367926(3-((4-(1-oxoisoindolin-4- yl)-2-sulfamoyl-3-(1H- t...)
Affinity DataIC50:  0.137nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent