BDBM3680 4-anilinopyrimido[5,4-d]pyrimidine deriv. 4a::6-Chloro-4-(phenylamino)pyrimido[5,4-d]pyrimidine::6-chloro-N-phenyl-[1,3]diazino[5,4-d]pyrimidin-4-amine

SMILES Clc1ncc2ncnc(Nc3ccccc3)c2n1

InChI Key InChIKey=MBZZMOBHTIEAEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3680   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM3680(4-anilinopyrimido[5,4-d]pyrimidine deriv. 4a | 6-C...)
Affinity DataIC50:  2.55E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed