BDBM368058 3-((4′-(Cyclopropanesulfonamido)-3-sulfamoyl-2-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)sulfonyl)-N-cyclopropylazetidine-1-carboxamide and 3-((4′-(cyclopropanesulfonamido)-3-sulfamoyl-2-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)sulfonyl)azetidine-1-carboxamide::US10227331, Example 245::US10227331, Example 246
SMILES NS(=O)(=O)c1c(ccc(-c2ccc(NS(=O)(=O)C3CC3)cc2)c1-c1nn[nH]n1)S(=O)(=O)C1CN(C1)C(=O)NC1CC1
InChI Key InChIKey=JYJIYIXQSOMJKY-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 368058
Affinity DataIC50: 0.126nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.386nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.139nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.103nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.327nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.218nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair