BDBM368108 3-(2-amino-4-cyano-1H-benzo[d]imidazol-7-yl)-6-((2-aminoethyl)sulfonyl)-2-(1H-tetrazol-5-yl)benzenesulfonamide::US10227331, Example 295

SMILES NCCS(=O)(=O)c1ccc(-c2ccc(C#N)c3nc(N)[nH]c23)c(-c2nnn[nH]2)c1S(N)(=O)=O

InChI Key InChIKey=AXNVDSSAHQBMDO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 368108   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM368108(3-(2-amino-4-cyano-1H-benzo[d]imidazol-7-yl)-6-((2...)
Affinity DataIC50:  1.22nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM368108(3-(2-amino-4-cyano-1H-benzo[d]imidazol-7-yl)-6-((2...)
Affinity DataIC50:  0.105nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM368108(3-(2-amino-4-cyano-1H-benzo[d]imidazol-7-yl)-6-((2...)
Affinity DataIC50:  0.116nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent