BDBM368192 (R)-6-((3-amino-2-hydroxypropyl)sulfonyl)-3-(2-amino-6-iodo-1H-benzo[d]imidazol-4-yl)-2-(2H-tetrazol-5-yl)benzenesulfonamide::US10227331, Example 379

SMILES NC[C@@H](O)CS(=O)(=O)c1ccc(-c2cc(I)cc3[nH]c(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key InChIKey=RTKRLHZRUKUNSA-KGSKPCQNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 368192   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM368192((R)-6-((3-amino-2-hydroxypropyl)sulfonyl)-3-(2-ami...)
Affinity DataIC50:  0.170nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM368192((R)-6-((3-amino-2-hydroxypropyl)sulfonyl)-3-(2-ami...)
Affinity DataIC50:  0.123nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM368192((R)-6-((3-amino-2-hydroxypropyl)sulfonyl)-3-(2-ami...)
Affinity DataIC50:  0.0810nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent