BDBM3683 4-anilinopyrimido[5,4-d]pyrimidine deriv. 5b::6-Amino-4-[(3-bromophenyl)amino]pyrimido[5,4-d]pyrimidine::8-N-(3-bromophenyl)-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine

SMILES Nc1ncc2ncnc(Nc3cccc(Br)c3)c2n1

InChI Key InChIKey=SJVLDEFAHRZRJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3683   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM3683(4-anilinopyrimido[5,4-d]pyrimidine deriv. 5b | 6-A...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM3683(4-anilinopyrimido[5,4-d]pyrimidine deriv. 5b | 6-A...)
Affinity DataIC50:  1.5nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed