BDBM372130 (R) or (S)-8-(1H-indazole-5-carbonyl)-3-(2-oxo-2-(3-(trifluoromethyl)piperazin-1-yl)ethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::US10239876, Example 153::US10435407, Example 153
SMILES FC(F)(F)[C@H]1CN(CCN1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 372130
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 41.9nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Affinity DataIC50: 41.9nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair