BDBM372159 6-(2,6- dimethylphenyl)- N-(3- morpholinophenyl)- 5H-pyrrolo[3,2- d ]pyrimidin-2- amine::US10239881, Example A12::US10875863, Example A12

SMILES Cc1cccc(C)c1-c1cc2nc(Nc3cccc(c3)N3CCOCC3)ncc2[nH]1

InChI Key InChIKey=ICKWVCXDMJAIEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372159   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM372159(6-(2,6- dimethylphenyl)- N-(3- morpholinophenyl)- ...)
Affinity DataIC50: <100nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM372159(6-(2,6- dimethylphenyl)- N-(3- morpholinophenyl)- ...)
Affinity DataIC50: <100nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent