BDBM372162 N-(4- (morpholino- methyl) phenyl)-6-(o-tolyl)- 5H-pyrrolo[3,2-d] pyrimidin-2-amine::US10239881, Example A15::US10875863, Example A15

SMILES Cc1ccccc1-c1cc2nc(Nc3ccc(CN4CCOCC4)cc3)ncc2[nH]1

InChI Key InChIKey=ONSCGBZIDKPAFU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372162   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM372162(N-(4- (morpholino- methyl) phenyl)-6-(o-tolyl)- 5H...)
Affinity DataIC50: <100nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM372162(N-(4- (morpholino- methyl) phenyl)-6-(o-tolyl)- 5H...)
Affinity DataIC50: <100nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent