BDBM373068 US10851080, Example 16::US9896435, Example 16

SMILES CCOc1ncc(cn1)-c1nn(c(NC(=O)N[C@@H]2CN(CCOC)C[C@H]2c2cc(F)cc(F)c2)c1C)-c1ccccc1

InChI Key InChIKey=KFQWLAXYPQROSD-IZZNHLLZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373068   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM373068(US10851080, Example 16 | US9896435, Example 16)
Affinity DataIC50: <100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM373068(US10851080, Example 16 | US9896435, Example 16)
Affinity DataIC50: <100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent