BDBM373078 US10323022, Example 604::US10851080, Example 26::US9896435, Example 26

SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccccc2)-c2ccc(=O)n(C)c2)[C@@H](C1)c1cc(F)c(F)c(F)c1

InChI Key InChIKey=FUOGGKZVABGZIJ-WIOPSUGQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 373078   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM373078(US10323022, Example 604 | US10851080, Example 26 |...)
Affinity DataIC50: <100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM373078(US10323022, Example 604 | US10851080, Example 26 |...)
Affinity DataIC50: <100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM373078(US10323022, Example 604 | US10851080, Example 26 |...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent