BDBM373370 ((2S,3R)-2-(((5-Fluorobenzo[d]oxazol-2-yl)amino)methyl)-3-methylpiperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone::US9896452, Ex. A129

SMILES C[C@@H]1CCCN([C@@H]1CNc1nc2cc(F)ccc2o1)C(=O)c1cc(C)ccc1-n1nccn1

InChI Key InChIKey=XYJCAEKTDPOHKG-IIBYNOLFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373370   

TargetOrexin receptor type 2(Homo sapiens (Human))
Eolas Therapeutics

US Patent
LigandPNGBDBM373370(((2S,3R)-2-(((5-Fluorobenzo[d]oxazol-2-yl)amino)me...)
Affinity DataIC50:  100nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Eolas Therapeutics

US Patent
LigandPNGBDBM373370(((2S,3R)-2-(((5-Fluorobenzo[d]oxazol-2-yl)amino)me...)
Affinity DataIC50:  3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent