BDBM374327 (6-(6-(6-((S)-1-aminobutyl)pyridin-2-yl)-4-((2S,5R)-5-methyltetrahydrofuran-2-yl)-1H-indazol-1-yl)pyridin-2-yl)methanol::US10246456, Example 479::US10577367, Example 479

SMILES CCC[C@H](N)c1cccc(n1)-c1cc([C@@H]2CC[C@@H](C)O2)c2cnn(-c3cccc(CO)n3)c2c1

InChI Key InChIKey=VTXXROMRFCHKQI-DRKZVIBPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 374327   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374327((6-(6-(6-((S)-1-aminobutyl)pyridin-2-yl)-4-((2S,5R...)
Affinity DataIC50: <100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374327((6-(6-(6-((S)-1-aminobutyl)pyridin-2-yl)-4-((2S,5R...)
Affinity DataIC50: <100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent